SPECIFIC SERUM IMMUNOGLOBULIN G AGAINST CHLAMYDIA PNEUMONIAE IN HEALTHY CHILDREN AND ADULTS IN SOUTH-EAST OF IRAN

Chlamydia pneumoniae (C. pneumonia) is an obligate intracellular bacterium and recognized as a risk factor for several diseases such as asthma, atherosclerosis and arthritis. The aim of this study was to determine the seroprevalence of C. pneumonia in healthy subjects in different age groups. The se...

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Veröffentlicht in:	Journal of Ayub Medical College, Abbottabad Abbottabad, 2015-04, Vol.27 (2), p.264-267
Hauptverfasser:	Nemati, Maryam, Mirzaee, Vahid, Shaabani, Ziba, Zarrin, Moein, Mirabdolahi, Sayed Ali, Bagheri-Jamebozorgi, Masoomeh, Rezayati, Mohammad-Taghi, Jafarzadeh, Abdollah
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibodies, Anti-Idiotypic - blood Antibodies, Anti-Idiotypic - immunology Child Child, Preschool Chlamydophila Infections - blood Chlamydophila Infections - epidemiology Chlamydophila Infections - immunology Chlamydophila pneumoniae - immunology Enzyme-Linked Immunosorbent Assay Female Humans Immunoglobulin G - immunology Iran - epidemiology Male Middle Aged Pneumonia, Bacterial - blood Pneumonia, Bacterial - epidemiology Pneumonia, Bacterial - immunology Prevalence Reference Values Retrospective Studies Risk Factors Seroepidemiologic Studies Young Adult
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Zusammenfassung:	Chlamydia pneumoniae (C. pneumonia) is an obligate intracellular bacterium and recognized as a risk factor for several diseases such as asthma, atherosclerosis and arthritis. The aim of this study was to determine the seroprevalence of C. pneumonia in healthy subjects in different age groups. The serum levels of anti C. pneumonia IgG were measured by using of ELISA. Totally, 630 subjects (164 children and 466 adults) were included into study. The seroprevalence and the mean titer of anti C. pneumonia antibody were 11.3% and 14.48?2.18 RU/mL; at age 510 years, 15% and 17.47 +/- 2.40 RU/mL at age 11-20 years, 21% and 25.15 +/- 4.56 RU/mL at age 21-30 years group, 40% and 53.77 +/- 6.40 RU/mL at age 31-40 years, 94% and 146.41 +/- 8.95 RU/mL at age 41-50 years, 98% and 153.59 +/- 10.38 RU/mL at age 51-60 years, 96% and 138.80 +/- 12.78 RU/mL at age 61-70 years, respectively. The differences of the seroprevalence and the mean titer of anti C. pneumonia antibody between age groups were significant (p
ISSN:	1025-9589