Flicker electroretinograms before and after intravitreal ranibizumab injection in eyes with central retinal vein occlusion

Purpose To compare the amplitudes and implicit times of the flicker electroretinograms before and after an intravitreal injection of ranibizumab (IVR) in eyes with a central retinal vein occlusion (CRVO). Methods We reviewed the medical records of 15 consecutive patients who had macular oedema secondary to CRVO and had received an IVR at the Nagoya University Hospital from November 2013 to July 2014. Flicker ERGs were recorded with both the RETeval™ system and a conventional ERG system before the IVR. One month after the IVR, recordings were repeated with only the RETeval™ system. Results The mean implicit times of the flicker ERGs of the affected eyes recorded with the RETeval™ system were significantly longer than that of the fellow eyes (32.2 ± 2.6 msec versus 28.1 ± 1.2 msec, p