Myelodysplastic syndromes in South America: A multinational study of 1080 patients

There are previously reported data describing differences between Asian and European patients with Myelodysplastic Syndromes (MDS), few direct comparisons based on cancer registration characteristics or using cohorts to validate scoring systems. This is the first study from South‐America, which atte...

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Veröffentlicht in:American journal of hematology 2015-10, Vol.90 (10), p.851-858
Hauptverfasser: Belli, Carolina B., Pinheiro, Ronald Feitosa, Bestach, Yesica, Larripa, Irene B., da Silva Tanizawa, Roberta Sandra, Alfonso, Graciela, Gonzalez, Jacqueline, Rosenhain, Mariana, Watman, Nora, Cavalcante de Andrade Silva, Marcela, Negri Aranguren, Pedro, García Rivello, Hernán, Magalhaes, Silvia M.M., Valladares, Ximena, Undurraga, María S., Velloso, Elvira R.P.
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Sprache:eng
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Zusammenfassung:There are previously reported data describing differences between Asian and European patients with Myelodysplastic Syndromes (MDS), few direct comparisons based on cancer registration characteristics or using cohorts to validate scoring systems. This is the first study from South‐America, which attempts to describe demographic, clinical features, and outcome of MDS patients. We retrospectively analyzed 1,080 patients with de novo MDS from Argentina (635), Brazil (345), and Chile (100). Chilean patients were younger (P = 0.001) with female preponderance (P = 0.071). Brazilian series showed a higher predominance of RARS subtype regarding FAB and WHO classifications (P 
ISSN:0361-8609
1096-8652
DOI:10.1002/ajh.24097