Utilizing the MOGE(S) Classification for Predicting Prognosis in Dilated Cardiomyopathy

[...]gene-specific treatments are not available for cardiomyopathic disorders, with a few exceptions for phenocopies; these include storage diseases with cardiac involvement in which disease-specific intervention has become available (7). [...]due to the small sample size and the relatively low even...

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Veröffentlicht in:	Journal of the American College of Cardiology 2015-09, Vol.66 (12), p.1324-1326
Hauptverfasser:	Dec, G. William, MD, Arbustini, Eloisa, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiology Cardiomyopathy Cardiomyopathy, Dilated - classification Cardiomyopathy, Dilated - etiology Cardiovascular Classification Deoxyribonucleic acid dilated cardiomyopathy Disease DNA Female Gene-Environment Interaction Genes Genomes Genotype & phenotype Heart attacks Humans Internal Medicine Male MOGE(S) classification Mortality Mutation prognosis
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Zusammenfassung:	[...]gene-specific treatments are not available for cardiomyopathic disorders, with a few exceptions for phenocopies; these include storage diseases with cardiac involvement in which disease-specific intervention has become available (7). [...]due to the small sample size and the relatively low event rates, the study had insufficient power to perform multivariable modeling to test for independent predictors of outcome.
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2015.06.1335