Association analysis of the IL-1 gene cluster polymorphisms with aggressive and chronic periodontitis in the Algerian population

Association analysis of the IL-1 gene cluster polymorphisms with aggressive and chronic periodontitis in the Algerian population

Highlights • Association between two polymorphisms of IL-1 gene cluster and the aggressive and chronic periodontitis risk was assessed. • A case control study was performed on Algerians. • IL-1B (C + 3954T) and IL-1A (C − 889T) polymorphisms were genotyped. • The association was found between these...

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Veröffentlicht in:Archives of oral biology 2015-10, Vol.60 (10), p.1463-1470
Hauptverfasser: Boukortt, Kawther Nourelhouda, Saidi-Ouahrani, Nadjia, Boukerzaza, Boubaker, Ouhaibi-Djellouli, Hadjira, Hachmaoui, Khalida, Benaissa, Fatima Zohra, Taleb, Leila, Drabla-Ouahrani, Hayet, Deba, Tahria, Ouledhamou, Sid Ahmed, Mehtar, Nadhera, Boudjema, Abdellah
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Advanced Basic Science
Aggressive Periodontitis
Algeria - epidemiology
Algerian population
Alleles
Case-Control Studies
Chronic periodontitis
Chronic Periodontitis - epidemiology
Chronic Periodontitis - genetics
Dental Plaque Index
Dentistry
Female
Gene
Gene Frequency
Genetics, Population
Genotype
Haplotypes
Humans
Interleukin-1
Interleukin-1alpha - genetics
Interleukin-1beta - genetics
Male
Middle Aged
Multigene Family
Polymorphism
Polymorphism, Single Nucleotide
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Beschreibung
Zusammenfassung:Highlights • Association between two polymorphisms of IL-1 gene cluster and the aggressive and chronic periodontitis risk was assessed. • A case control study was performed on Algerians. • IL-1B (C + 3954T) and IL-1A (C − 889T) polymorphisms were genotyped. • The association was found between these 2 polymorphisms and aggressive periodontitis.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2015.06.018