Allergic and immunotoxic effects of calcium ketopantoyl aminobutyrate

We studied the allergic and immunotoxic effects of a new promising medicinal preparation calcium ketopantoyl aminobutyrate. Calcium ketopantoyl aminobutyrate produced no negative effects on general mechanisms of humoral and cellular immunity. This preparation did not modulate the anaphylactic reacti...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2005-04, Vol.139 (4), p.434-436
Hauptverfasser:	Karaev, A L, Treshchalin, I D, Bodyagin, D A, Pereverzeva, E R, Kozlova, G S, Gunar, V I
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminobutyrates - toxicity Animals Antibody Formation - drug effects Guinea Pigs Hypersensitivity Immune System - drug effects Immunity, Cellular - drug effects Mice Mice, Inbred C57BL Mice, Inbred CBA Pantothenic Acid - analogs & derivatives Pantothenic Acid - toxicity
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Beschreibung
Zusammenfassung:	We studied the allergic and immunotoxic effects of a new promising medicinal preparation calcium ketopantoyl aminobutyrate. Calcium ketopantoyl aminobutyrate produced no negative effects on general mechanisms of humoral and cellular immunity. This preparation did not modulate the anaphylactic reaction to bovine serum, exhibited no mitostatic and lymphotoxic properties, had no effect on the delayed-type hypersensitivity response, and did not produce active cutaneous anaphylactic reaction.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-005-0315-1