Sex determines cardiovascular hemodynamics in hypertension
The aim of this study was to evaluate the influence of sex on cardiovascular hemodynamics and heart remodeling in 144 patients with arterial hypertension that underwent: (1) echocardiography (that is, indices of left ventricular diastolic function: e′, E/e′), (2) impedance cardiography (that is, sys...
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Veröffentlicht in: | Journal of human hypertension 2015-10, Vol.29 (10), p.610-617 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The aim of this study was to evaluate the influence of sex on cardiovascular hemodynamics and heart remodeling in 144 patients with arterial hypertension that underwent: (1) echocardiography (that is, indices of left ventricular diastolic function: e′, E/e′), (2) impedance cardiography (that is, systemic vascular resistance (SVR), total artery compliance (TAC) and Heather index (HI)) and (3) applanation tonometry (augmentation index (AI), central systolic and diastolic blood pressure (CSBP, CDBP), central pulse pressure (CPP)). Women, in comparison with men, revealed to have: (1) stiffer arteries—lower TAC (1.93±0.55 vs 2.16±0.59 ml per mm Hg;
P
=0.025), higher CSBP (128.7±14.9 vs 123.4±13.2 mm Hg;
P
=0.036), CPP (39.9±9.5 vs 33.8±9.0 mm Hg;
P
=0.0002), AI (31.5±8.7 vs 17.5±12.7%;
P |
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ISSN: | 0950-9240 1476-5527 |
DOI: | 10.1038/jhh.2014.134 |