Disulfiram-like Reaction with Ornidazole

Disulfiram-like Reaction with Ornidazole

Common side effects of the ornidazole include somnolence, headache, and gastrointestinal disturbances; more severe side effects include dizziness, seizures, rigidity, temporary loss of consciousness, and neuropathies [1]. [...]we believe that the symptoms in the case that we presented are not due to...

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Veröffentlicht in:The American journal of emergency medicine 2015-09, Vol.33 (9), p.1330.e7-1330.e8
Hauptverfasser: Guler, Sertac, MD, Aytar, Halit, MD, Soyuduru, Murat, MD, Ramadan, Hayri, MD
Format: Artikel
Sprache:eng
Schlagworte:
Acetaldehyde Dehydrogenase Inhibitors - adverse effects
Adult
Aldehydes
Antibiotics
Antitrichomonal Agents - adverse effects
Anxiety
Cardiac arrhythmia
Dehydrogenases
Disulfiram - adverse effects
Emergency
Emergency medical care
Enzymes
Fluids
Food-Drug Interactions
Humans
Male
Ornidazole - adverse effects
Rigidity
Side effects
Substance abuse treatment
Wine
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Zusammenfassung:Common side effects of the ornidazole include somnolence, headache, and gastrointestinal disturbances; more severe side effects include dizziness, seizures, rigidity, temporary loss of consciousness, and neuropathies [1]. [...]we believe that the symptoms in the case that we presented are not due to the drug's side effects, but rather to a DLR. [...]when an ornidazole, such as metronidazole, is used in combination with alcohol, it leads to DLR.
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2015.03.022