Thermal decomposition of new chlorido(p-cymene) ruthenium(II) complexes containing N-alkylphenothiazines

The thermal decomposition of [RuCl 2 (η 6 - p -cymene)] 2 ( 1 ) and its biologically active N -alkylphenothiazine compounds of composition L[RuCl 3 (η 6 - p -cymene)] where L = CPH + ( 2 ), TFH + ·HCl ( 3 ), and TRH + ( 4 ) (chlorpromazine hydrochloride, CP·HCl; trifluoperazine dihydrochloride, TF·2HCl; and thioridazine hydrochloride, TR·HCl, respectively) has been studied. The crystal and molecular structure of compound 3 was determined earlier by single crystal X-ray diffraction analysis. The thermal data were collected by simultaneous TG/DSC measurements. For evolved gas detection, the qualitative reaction of chlorides with AgNO 3 in an acidic solution was applied. The measurements were carried out in the temperature range to 700 °C in nitrogen atmosphere. Compounds of L[RuCl 3 (η 6 - p -cymene)] crystallize with water or water/2-propanole. On the basis of thermal data, the trend in the solvent bonding energies was assessed.