Plant phytochemicals: potential anticancer agents against gastric cancer

Highlights • Consumption of isothiocyanates is epidemiologically linked to reduced risk gastric cancer risk. • ITC may prevent gastric cancer by interfering with multiple tumor promoting factors. • ITC may reduce colonization of Helicobacter pylori in human stomach. • ITC leads to loss of microtubul...

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Veröffentlicht in:Current opinion in pharmacology 2014-12, Vol.19, p.6-10
Hauptverfasser: Øverby, Anders, Zhao, Chun-Mei, Chen, Duan
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Chen, Duan
description Highlights • Consumption of isothiocyanates is epidemiologically linked to reduced risk gastric cancer risk. • ITC may prevent gastric cancer by interfering with multiple tumor promoting factors. • ITC may reduce colonization of Helicobacter pylori in human stomach. • ITC leads to loss of microtubules and increase in apoptosis in gastric cancer cells.
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subjects Animals
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Anticarcinogenic Agents - pharmacology
Anticarcinogenic Agents - therapeutic use
Helicobacter pylori
Helicobacter pylori - drug effects
Humans
Internal Medicine
Isothiocyanates - pharmacology
Isothiocyanates - therapeutic use
Medical Education
Phytochemicals - pharmacology
Phytochemicals - therapeutic use
Stomach - microbiology
Stomach Neoplasms - prevention & control
Vegetables
title Plant phytochemicals: potential anticancer agents against gastric cancer
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