Plant phytochemicals: potential anticancer agents against gastric cancer
Highlights • Consumption of isothiocyanates is epidemiologically linked to reduced risk gastric cancer risk. • ITC may prevent gastric cancer by interfering with multiple tumor promoting factors. • ITC may reduce colonization of Helicobacter pylori in human stomach. • ITC leads to loss of microtubul...
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Veröffentlicht in: | Current opinion in pharmacology 2014-12, Vol.19, p.6-10 |
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description | Highlights • Consumption of isothiocyanates is epidemiologically linked to reduced risk gastric cancer risk. • ITC may prevent gastric cancer by interfering with multiple tumor promoting factors. • ITC may reduce colonization of Helicobacter pylori in human stomach. • ITC leads to loss of microtubules and increase in apoptosis in gastric cancer cells. |
doi_str_mv | 10.1016/j.coph.2014.05.010 |
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subjects | Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Anticarcinogenic Agents - pharmacology Anticarcinogenic Agents - therapeutic use Helicobacter pylori Helicobacter pylori - drug effects Humans Internal Medicine Isothiocyanates - pharmacology Isothiocyanates - therapeutic use Medical Education Phytochemicals - pharmacology Phytochemicals - therapeutic use Stomach - microbiology Stomach Neoplasms - prevention & control Vegetables |
title | Plant phytochemicals: potential anticancer agents against gastric cancer |
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