Plant phytochemicals: potential anticancer agents against gastric cancer

Highlights • Consumption of isothiocyanates is epidemiologically linked to reduced risk gastric cancer risk. • ITC may prevent gastric cancer by interfering with multiple tumor promoting factors. • ITC may reduce colonization of Helicobacter pylori in human stomach. • ITC leads to loss of microtubul...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in pharmacology 2014-12, Vol.19, p.6-10
Hauptverfasser:	Øverby, Anders, Zhao, Chun-Mei, Chen, Duan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Anticarcinogenic Agents - pharmacology Anticarcinogenic Agents - therapeutic use Helicobacter pylori Helicobacter pylori - drug effects Humans Internal Medicine Isothiocyanates - pharmacology Isothiocyanates - therapeutic use Medical Education Phytochemicals - pharmacology Phytochemicals - therapeutic use Stomach - microbiology Stomach Neoplasms - prevention & control Vegetables
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Consumption of isothiocyanates is epidemiologically linked to reduced risk gastric cancer risk. • ITC may prevent gastric cancer by interfering with multiple tumor promoting factors. • ITC may reduce colonization of Helicobacter pylori in human stomach. • ITC leads to loss of microtubules and increase in apoptosis in gastric cancer cells.
ISSN:	1471-4892 1471-4973
DOI:	10.1016/j.coph.2014.05.010