Clinical Presentation and Five-Year Therapeutic Management of Very Early-Onset Inflammatory Bowel Disease in a Large North American Cohort

Objective To evaluate the presentation, therapeutic management, and long-term outcome of children with very early-onset (VEO) (≤5 years of age) inflammatory bowel disease (IBD). Study design Data were obtained from an inception cohort of 1928 children with IBD enrolled in a prospective observational...

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Veröffentlicht in:	The Journal of pediatrics 2015-09, Vol.167 (3), p.527-532.e3
Hauptverfasser:	Oliva-Hemker, Maria, MD, Hutfless, Susan, PhD, Al Kazzi, Elie S., MD, MPH, Lerer, Trudy, MS, Mack, David, MD, LeLeiko, Neal, MD, PhD, Griffiths, Anne, MD, Cabrera, Jose, MD, Otley, Anthony, MD, Rick, James, MD, Bousvaros, Athos, MD, Rosh, Joel, MD, Grossman, Andrew, MD, Saeed, Shehzad, MD, Kay, Marsha, MD, Carvalho, Ryan, MD, Keljo, David, MD, PhD, Pfefferkorn, Marian, MD, Faubion, William, MD, Kappelman, Michael, MD, Sudel, Boris, MD, Schaefer, Marc E., MD, Markowitz, James, MD, Hyams, Jeffrey S., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age of Onset Child Child, Preschool Disease Progression Female Follow-Up Studies Humans Infant Inflammatory Bowel Diseases - diagnosis Inflammatory Bowel Diseases - therapy Male North America Pediatrics Phenotype Prognosis Prospective Studies Registries
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Zusammenfassung:	Objective To evaluate the presentation, therapeutic management, and long-term outcome of children with very early-onset (VEO) (≤5 years of age) inflammatory bowel disease (IBD). Study design Data were obtained from an inception cohort of 1928 children with IBD enrolled in a prospective observational registry at multiple centers in North America. Results One hundred twelve children were ≤5 years of age with no child enrolled at
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2015.04.045