Iron(III)-Selective Chelation-Enhanced Fluorescence Sensing for In Vivo Imaging Applications
A “turn‐on” pattern Fe3+‐selective fluorescent sensor was synthesized and characterized that showed high fluorescence discrimination of Fe3+ over Fe2+ and other tested ions. With a 62‐fold fluorescence enhancement towards Fe3+, the probe was employed to detect Fe3+ in vivo in HeLa cells and Caenorha...
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Veröffentlicht in: | Chemistry, an Asian journal an Asian journal, 2015-09, Vol.10 (9), p.1898-1902 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A “turn‐on” pattern Fe3+‐selective fluorescent sensor was synthesized and characterized that showed high fluorescence discrimination of Fe3+ over Fe2+ and other tested ions. With a 62‐fold fluorescence enhancement towards Fe3+, the probe was employed to detect Fe3+ in vivo in HeLa cells and Caenorhabditis elegans, and it was also successfully used to elucidate Fe3+ enrichment and exchange infected by innexin3 (Inx3) in hemichannel‐closed Sf9 cells.
Into the light: A “turn‐on” pattern Fe3+‐selective fluorescent sensor has been synthesized and characterized that showed high fluorescence discrimination of Fe3+ over Fe2+ and other tested ions. With a 62‐fold fluorescence enhancement towards Fe3+, the probe was employed to detect Fe3+ in vivo in HeLa cells and Caenorhabditis elegans, and it was also successfully used to elucidate Fe3+ enrichment and exchange infected by innexin3 (Inx3) in hemichannel‐closed Sf9 cells. |
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ISSN: | 1861-4728 1861-471X |
DOI: | 10.1002/asia.201500415 |