Skin microvascular endothelial function as a biomarker in cardiovascular diseases?
Skin microvascular endothelial function is impaired in many cardiovascular diseases, and could be therefore considered as a representative vascular bed. However, today, available evidence allows considering skin microvascular endothelial function neither as a diagnostic biomarker nor as a prognostic...
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Veröffentlicht in: | Pharmacological reports 2015-08, Vol.67 (4), p.803-810 |
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creator | Hellmann, Marcin Roustit, Matthieu Cracowski, Jean-Luc |
description | Skin microvascular endothelial function is impaired in many cardiovascular diseases, and could be therefore considered as a representative vascular bed. However, today, available evidence allows considering skin microvascular endothelial function neither as a diagnostic biomarker nor as a prognostic biomarker in cardiovascular diseases. Large follow-up studies using standardized methods should now be conducted to assess the potential predictive value of skin microvascular function in cardiovascular diseases. |
doi_str_mv | 10.1016/j.pharep.2015.05.008 |
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However, today, available evidence allows considering skin microvascular endothelial function neither as a diagnostic biomarker nor as a prognostic biomarker in cardiovascular diseases. 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Large follow-up studies using standardized methods should now be conducted to assess the potential predictive value of skin microvascular function in cardiovascular diseases.</description><subject>Animals</subject><subject>Cardiovascular Diseases - diagnosis</subject><subject>Cardiovascular Diseases - physiopathology</subject><subject>Case-Control Studies</subject><subject>Drug Safety and Pharmacovigilance</subject><subject>Endothelium</subject><subject>Endothelium, Vascular - pathology</subject><subject>Endothelium, Vascular - physiology</subject><subject>Humans</subject><subject>Laser Doppler</subject><subject>Laser speckle contrast imaging</subject><subject>Laser-Doppler Flowmetry - methods</subject><subject>Microvessels - pathology</subject><subject>Pharmacotherapy</subject><subject>Pharmacy</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Reactivity tests</subject><subject>Review Article</subject><subject>Skin - blood supply</subject><subject>Skin - pathology</subject><subject>Skin microcirculation</subject><subject>Vasodilation - physiology</subject><issn>1734-1140</issn><issn>2299-5684</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxTAQhYMoen38A5Eu3fQ6SZM22SgivkAQfKxDmkw11972mrSC_95IfewUBmYg5zvhHEL2Kcwp0PJoMV89m4CrOQMq5pAG5BqZMaZULkrJ18mMVgXPKeWwRbZjXABwygqxSbZYWTDKJJ-Ru_sX32VLb0P_ZqIdWxMy7Fw_PGPrTZs1Y2cH33eZiZnJat8vTXjBkCXImuD8L-V8RBMxnuySjca0Efe-9g55vDh_OLvKb24vr89Ob3LLKznkkjqQ6UTDVC1LVSimsABWNZZxKIVQVVM7wymWSCsnqrpEsFYqY6GohCh2yOHkuwr964hx0EsfLbat6bAfo6YVSKkEL3iS8kmaYsYYsNGr4FOSd01Bf7apF3pqU3-2qSENyIQdfP0w1kt0P9B3fUkgJkFMT90TBr3ox9Cl1P8ZH08cpn7efOKi9dhZdD6gHbTr_d8GH3KvmcQ</recordid><startdate>201508</startdate><enddate>201508</enddate><creator>Hellmann, Marcin</creator><creator>Roustit, Matthieu</creator><creator>Cracowski, Jean-Luc</creator><general>Elsevier Urban & Partner Sp. z o.o</general><general>Springer International Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201508</creationdate><title>Skin microvascular endothelial function as a biomarker in cardiovascular diseases?</title><author>Hellmann, Marcin ; Roustit, Matthieu ; Cracowski, Jean-Luc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-81d08c47ea29b8693929e3027fc24065597fbda41e6e17d57b6e0cc89ac037553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Animals</topic><topic>Cardiovascular Diseases - diagnosis</topic><topic>Cardiovascular Diseases - physiopathology</topic><topic>Case-Control Studies</topic><topic>Drug Safety and Pharmacovigilance</topic><topic>Endothelium</topic><topic>Endothelium, Vascular - pathology</topic><topic>Endothelium, Vascular - physiology</topic><topic>Humans</topic><topic>Laser Doppler</topic><topic>Laser speckle contrast imaging</topic><topic>Laser-Doppler Flowmetry - methods</topic><topic>Microvessels - pathology</topic><topic>Pharmacotherapy</topic><topic>Pharmacy</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Reactivity tests</topic><topic>Review Article</topic><topic>Skin - blood supply</topic><topic>Skin - pathology</topic><topic>Skin microcirculation</topic><topic>Vasodilation - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hellmann, Marcin</creatorcontrib><creatorcontrib>Roustit, Matthieu</creatorcontrib><creatorcontrib>Cracowski, Jean-Luc</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmacological reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hellmann, Marcin</au><au>Roustit, Matthieu</au><au>Cracowski, Jean-Luc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Skin microvascular endothelial function as a biomarker in cardiovascular diseases?</atitle><jtitle>Pharmacological reports</jtitle><stitle>Pharmacol. 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subjects | Animals Cardiovascular Diseases - diagnosis Cardiovascular Diseases - physiopathology Case-Control Studies Drug Safety and Pharmacovigilance Endothelium Endothelium, Vascular - pathology Endothelium, Vascular - physiology Humans Laser Doppler Laser speckle contrast imaging Laser-Doppler Flowmetry - methods Microvessels - pathology Pharmacotherapy Pharmacy Randomized Controlled Trials as Topic Reactivity tests Review Article Skin - blood supply Skin - pathology Skin microcirculation Vasodilation - physiology |
title | Skin microvascular endothelial function as a biomarker in cardiovascular diseases? |
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