Prognostic Impact of Anemia in Patients With Chronic Heart Failure　– With Special Reference to Clinical Background: Report From the CHART-2 Study

Prognostic Impact of Anemia in Patients With Chronic Heart Failure　– With Special Reference to Clinical Background: Report From the CHART-2 Study

Background:We aimed to elucidate the prognostic impact of anemia with special reference to the clinical background of patients with chronic heart failure (CHF).Methods and Results:We examined 4,646 consecutive patients with Stage C/D CHF registered in the Chronic Heart Failure Analysis and Registry...

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Veröffentlicht in:Circulation Journal 2015/08/25, Vol.79(9), pp.1984-1993
Hauptverfasser: Yamauchi, Takeshi, Sakata, Yasuhiko, Takada, Tsuyoshi, Nochioka, Kotaro, Miura, Masanobu, Tadaki, Soichiro, Ushigome, Ryoichi, Sato, Kenjiro, Onose, Takeo, Tsuji, Kanako, Abe, Ruri, Takahashi, Jun, Miyata, Satoshi, Shimokawa, Hiroaki, on behalf of the CHART-2 investigators
Format: Artikel
Sprache:eng
Schlagworte:
Adrenergic beta-Antagonists - administration & dosage
Age Factors
Aged
Aged, 80 and over
Anemia
Anemia - blood
Anemia - drug therapy
Anemia - etiology
Anemia - mortality
Anemia - physiopathology
Chronic Disease
Disease-Free Survival
Diuretics - administration & dosage
Etiology
Female
Follow-Up Studies
Glomerular Filtration Rate - drug effects
Heart failure
Heart Failure - complications
Heart Failure - drug therapy
Heart Failure - mortality
Heart Failure - physiopathology
Humans
Left ventricular ejection fraction
Male
Middle Aged
Natriuretic Peptide, Brain - blood
Prognosis
Prospective Studies
Stroke Volume - drug effects
Survival Rate
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Zusammenfassung:Background:We aimed to elucidate the prognostic impact of anemia with special reference to the clinical background of patients with chronic heart failure (CHF).Methods and Results:We examined 4,646 consecutive patients with Stage C/D CHF registered in the Chronic Heart Failure Analysis and Registry in the Tohoku District-2 (CHART-2) Study (n=10,219). Among them, 1,627 (35%) had anemia and were characterized by higher age (74 vs. 66 years), lower estimated glomerular filtration rate (52.8 vs. 66.1 ml/min/1.73 m2) and higher B-type natriuretic peptide levels (154.5 vs. 81.8 pg/ml) (all P
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-15-0174