Regulation of the rainbow trout metallothionein-A gene

Regulation of the rainbow trout metallothionein-A gene

In rainbow trout two metallothionein genes have been identified. The proximal promoter sequences have previously been sequenced and two metal responsive elements (MREs) have been identified in both genes (Zafarullah et al., 1988; Murphy et al., 1990). In the present study the distal part of the MT-A...

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Veröffentlicht in:Marine environmental research 1995, Vol.39 (1), p.117-120
Hauptverfasser: Kling, Peter, Olsson, Per-Erik
Format: Artikel
Sprache:eng
Schlagworte:
Freshwater
Oncorhynchus mykiss
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Zusammenfassung:In rainbow trout two metallothionein genes have been identified. The proximal promoter sequences have previously been sequenced and two metal responsive elements (MREs) have been identified in both genes (Zafarullah et al., 1988; Murphy et al., 1990). In the present study the distal part of the MT-A gene promoter region was sequenced in order to identify additional regulatory elements. Data is now presented demonstrating the presence of additional MREs in the MT-A gene as well as sequences with high similarity to AP1 consensus sequences.
ISSN:0141-1136
1879-0291
DOI:10.1016/0141-1136(94)00047-S