Ultrasensitive strategy based on PtPd nanodendrite/nano-flower-like@GO signal amplification for the detection of long non-coding RNA

Highly up-regulated in liver cancer (HULC) is a novel promising noninvasive biomarker for hepatocellular carcinoma (HCC), which is a kind of long non-coding RNAs (lncRNAs). But traditional methods limited HULC clinical detection for ownself drawbacks. Development a new HULC detection approach is urg...

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Veröffentlicht in:	Biosensors & bioelectronics 2015-12, Vol.74, p.214-221
Hauptverfasser:	Liu, Fei, Xiang, Guiming, Jiang, Dongneng, Zhang, Liqun, Chen, Xuemei, Liu, Linlin, Luo, Fukang, Li, Yi, Liu, Chang, Pu, Xiaoyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques - methods Biosensor Carcinoma, Hepatocellular - blood Carcinoma, Hepatocellular - diagnosis Electrochemical Techniques - methods Graphite - chemistry Highly up-regulated in liver cancer (HULC) Humans Limit of Detection Liver Neoplasms - blood Liver Neoplasms - diagnosis Long non-coding RNA (lncRNA) Nanostructures - chemistry Nanostructures - ultrastructure Palladium - chemistry Platinum - chemistry PtPd bimetallic nanodendrites/nanoflower-like clusters on graphene oxide (PtPd BND/BNF@GO) Reproducibility of Results RNA, Long Noncoding - analysis RNA, Long Noncoding - blood
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