Assessment of Molecular Markers in AML Patients: A Hospital-Based Study in Lebanon

Assessment of Molecular Markers in AML Patients: A Hospital-Based Study in Lebanon

Micro-Abstract We reviewed the files of 144 AML patients referred to Saint George Hospital-Lebanon for AML characterization. We determined the prevalence of different markers used in risk stratification. We found a higher prevalence of acute promyelocytic leukemia highlighting the possible role of g...

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Veröffentlicht in:Clinical lymphoma, myeloma and leukemia myeloma and leukemia, 2015-06, Vol.15, p.S80-S84
Hauptverfasser: El Halabi, Layal, Djaffar-Jureidini, Isabelle, Hakime, Noha, Saidy, Ghada, Chamseddine, Nabil
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Biomarkers, Tumor
Female
Hematology, Oncology and Palliative Medicine
Humans
Karyotype
Lebanon
Leukemia, Myeloid, Acute - genetics
Male
Mutation
Prevalence
Prognosis
Signal Transduction
Signaling Pathways
Targeted therapy
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Zusammenfassung:Micro-Abstract We reviewed the files of 144 AML patients referred to Saint George Hospital-Lebanon for AML characterization. We determined the prevalence of different markers used in risk stratification. We found a higher prevalence of acute promyelocytic leukemia highlighting the possible role of genetic predisposition and environmental factors. We discussed other markers for their role in prognostication and disease monitoring in AML patients.
ISSN:2152-2650
2152-2669
DOI:10.1016/j.clml.2015.02.011