Au-Catalyzed Pentannulation Reaction of Propargylic Esters Occurring at C(sp3)–H Site
A gold-catalyzed cascade cyclization reaction of easily accessible propargylic esters to cyclopentenones has been developed. This transformation features an unprecedented pentannulation reaction of propargylic esters which occurs at an unactivated C(sp3)–H site to efficiently produce functionalized...
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Veröffentlicht in: | Organic letters 2015-08, Vol.17 (16), p.4062-4065 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | A gold-catalyzed cascade cyclization reaction of easily accessible propargylic esters to cyclopentenones has been developed. This transformation features an unprecedented pentannulation reaction of propargylic esters which occurs at an unactivated C(sp3)–H site to efficiently produce functionalized mono-, bis-, and tricyclic cyclopentenones. |
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ISSN: | 1523-7060 1523-7052 |
DOI: | 10.1021/acs.orglett.5b01983 |