A chemocentric view of the natural product inventory

As the identification of previously undetected microbial biosynthetic pathways burgeons, there arises the question of how much new chemistry is yet to be found. This, in turn, devolves to: what kinds of biosynthetic enzymatic transformations are yet to be characterized?

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature chemical biology 2015-09, Vol.11 (9), p.620-624
1. Verfasser:	Walsh, Christopher T
Format:	Artikel
Sprache:	eng
Schlagworte:	631/114/2184 631/92/173 631/92/349 631/92/60 Alkaloids - biosynthesis Arabidopsis - chemistry Arabidopsis - enzymology Arabidopsis Proteins - chemistry Arabidopsis Proteins - metabolism Bacteria - chemistry Bacteria - enzymology Bacterial Proteins - chemistry Bacterial Proteins - metabolism Biochemical Engineering Biochemistry Biological Products - chemistry Biological Products - metabolism Bioorganic Chemistry Biosynthesis Cell Biology Chemistry Chemistry/Food Science commentary Cyclization Cytochrome P-450 Enzyme System - chemistry Cytochrome P-450 Enzyme System - metabolism Dimethylallyltranstransferase - chemistry Dimethylallyltranstransferase - metabolism Enzymes Fungal Proteins - chemistry Fungal Proteins - metabolism Fungi - chemistry Fungi - enzymology Microorganisms Peptide Synthases - chemistry Peptide Synthases - metabolism Polyketide Synthases - chemistry Polyketide Synthases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	As the identification of previously undetected microbial biosynthetic pathways burgeons, there arises the question of how much new chemistry is yet to be found. This, in turn, devolves to: what kinds of biosynthetic enzymatic transformations are yet to be characterized?
ISSN:	1552-4450 1552-4469
DOI:	10.1038/nchembio.1894