Microfluidic method for creating monodisperse viscous single emulsions via core–shell templating
Creating droplets with viscous media in microfluidic devices is extremely problematic due to the early onset of jetting. This report presents a method of creating highly monodisperse single emulsions of high viscosity (≈100 cP for both dispersed and continuous phases) using glass-based microfluidics...
Gespeichert in:
Veröffentlicht in: | Microfluidics and nanofluidics 2015-03, Vol.18 (3), p.383-390 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 390 |
---|---|
container_issue | 3 |
container_start_page | 383 |
container_title | Microfluidics and nanofluidics |
container_volume | 18 |
creator | Josephides, Dimitris N. Sajjadi, Shahriar |
description | Creating droplets with viscous media in microfluidic devices is extremely problematic due to the early onset of jetting. This report presents a method of creating highly monodisperse single emulsions of high viscosity (≈100 cP for both dispersed and continuous phases) using glass-based microfluidics. This method utilises a three-phase flow technique, where internal water droplets are introduced into a would-be-jetting oil stream forcing the system into a quasi-dripping regime to produce highly monodisperse core–shell drops that later rupture to form single drops. Emulsions with droplet diameters between 75 and 120 μm with a
C
v
|
doi_str_mv | 10.1007/s10404-014-1439-2 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1705064408</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1705064408</sourcerecordid><originalsourceid>FETCH-LOGICAL-c456t-ab90eab0b14d5131b2afedfc48c47da84bd8c2fcc39ce74f45eb3d02147595a43</originalsourceid><addsrcrecordid>eNp1kM1KxDAUhYsoOI4-gLuAGzfVm_a2TZci_sGIG12HNLmd6dA2NWkFd76Db-iTmHFERHCVwP3O4fBF0TGHMw5QnHsOCBgDx5hjWsbJTjTjOU9jLEvY_fmLZD868H4NgEXCYRZV9412tm6nxjSadTSurGG1dUw7UmPTL1lne2saP5DzxF4ar-3kmQ-Xlhh1U-sb2_twUExbRx9v735FbctG6ob2q-Ew2qtV6-no-51HT9dXj5e38eLh5u7yYhFrzPIxVlUJpCqoOJqMp7xKVE2m1ig0FkYJrIzQSa11WmoqsMaMqtRAwrHIykxhOo9Ot72Ds88T-VF2YW3YonoKmyUvIIMcEURAT_6gazu5PqyTPM-ECIzYFPItFQx576iWg2s65V4lB7mxLrfWZbAuN9ZlEjLJNuMD2y_J_Wr-N_QJCR2H9g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1658840884</pqid></control><display><type>article</type><title>Microfluidic method for creating monodisperse viscous single emulsions via core–shell templating</title><source>SpringerLink Journals</source><creator>Josephides, Dimitris N. ; Sajjadi, Shahriar</creator><creatorcontrib>Josephides, Dimitris N. ; Sajjadi, Shahriar</creatorcontrib><description>Creating droplets with viscous media in microfluidic devices is extremely problematic due to the early onset of jetting. This report presents a method of creating highly monodisperse single emulsions of high viscosity (≈100 cP for both dispersed and continuous phases) using glass-based microfluidics. This method utilises a three-phase flow technique, where internal water droplets are introduced into a would-be-jetting oil stream forcing the system into a quasi-dripping regime to produce highly monodisperse core–shell drops that later rupture to form single drops. Emulsions with droplet diameters between 75 and 120 μm with a
C
v
< 2 % were created at flow rates of up to 500 μl/h using this three-phase technique where similar emulsions using the standard two-phase technique could not be obtained. The rate of addition of internal droplets to induce a quasi-dripping mode was found to be similar to the dominant perturbation frequencies required to rupture a jet according to Plateau–Rayleigh instability theory.</description><identifier>ISSN: 1613-4982</identifier><identifier>EISSN: 1613-4990</identifier><identifier>DOI: 10.1007/s10404-014-1439-2</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Analytical Chemistry ; Biomedical Engineering and Bioengineering ; Emulsions ; Engineering ; Engineering Fluid Dynamics ; Flow rates ; Internal water ; Nanotechnology and Microengineering ; Research Paper</subject><ispartof>Microfluidics and nanofluidics, 2015-03, Vol.18 (3), p.383-390</ispartof><rights>Springer-Verlag Berlin Heidelberg 2014</rights><rights>Springer-Verlag Berlin Heidelberg 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c456t-ab90eab0b14d5131b2afedfc48c47da84bd8c2fcc39ce74f45eb3d02147595a43</citedby><cites>FETCH-LOGICAL-c456t-ab90eab0b14d5131b2afedfc48c47da84bd8c2fcc39ce74f45eb3d02147595a43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10404-014-1439-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10404-014-1439-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Josephides, Dimitris N.</creatorcontrib><creatorcontrib>Sajjadi, Shahriar</creatorcontrib><title>Microfluidic method for creating monodisperse viscous single emulsions via core–shell templating</title><title>Microfluidics and nanofluidics</title><addtitle>Microfluid Nanofluid</addtitle><description>Creating droplets with viscous media in microfluidic devices is extremely problematic due to the early onset of jetting. This report presents a method of creating highly monodisperse single emulsions of high viscosity (≈100 cP for both dispersed and continuous phases) using glass-based microfluidics. This method utilises a three-phase flow technique, where internal water droplets are introduced into a would-be-jetting oil stream forcing the system into a quasi-dripping regime to produce highly monodisperse core–shell drops that later rupture to form single drops. Emulsions with droplet diameters between 75 and 120 μm with a
C
v
< 2 % were created at flow rates of up to 500 μl/h using this three-phase technique where similar emulsions using the standard two-phase technique could not be obtained. The rate of addition of internal droplets to induce a quasi-dripping mode was found to be similar to the dominant perturbation frequencies required to rupture a jet according to Plateau–Rayleigh instability theory.</description><subject>Analytical Chemistry</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Emulsions</subject><subject>Engineering</subject><subject>Engineering Fluid Dynamics</subject><subject>Flow rates</subject><subject>Internal water</subject><subject>Nanotechnology and Microengineering</subject><subject>Research Paper</subject><issn>1613-4982</issn><issn>1613-4990</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp1kM1KxDAUhYsoOI4-gLuAGzfVm_a2TZci_sGIG12HNLmd6dA2NWkFd76Db-iTmHFERHCVwP3O4fBF0TGHMw5QnHsOCBgDx5hjWsbJTjTjOU9jLEvY_fmLZD868H4NgEXCYRZV9412tm6nxjSadTSurGG1dUw7UmPTL1lne2saP5DzxF4ar-3kmQ-Xlhh1U-sb2_twUExbRx9v735FbctG6ob2q-Ew2qtV6-no-51HT9dXj5e38eLh5u7yYhFrzPIxVlUJpCqoOJqMp7xKVE2m1ig0FkYJrIzQSa11WmoqsMaMqtRAwrHIykxhOo9Ot72Ds88T-VF2YW3YonoKmyUvIIMcEURAT_6gazu5PqyTPM-ECIzYFPItFQx576iWg2s65V4lB7mxLrfWZbAuN9ZlEjLJNuMD2y_J_Wr-N_QJCR2H9g</recordid><startdate>20150301</startdate><enddate>20150301</enddate><creator>Josephides, Dimitris N.</creator><creator>Sajjadi, Shahriar</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TB</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H96</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>L6V</scope><scope>M0S</scope><scope>M7S</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>S0W</scope><scope>7QH</scope><scope>7UA</scope><scope>C1K</scope></search><sort><creationdate>20150301</creationdate><title>Microfluidic method for creating monodisperse viscous single emulsions via core–shell templating</title><author>Josephides, Dimitris N. ; Sajjadi, Shahriar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c456t-ab90eab0b14d5131b2afedfc48c47da84bd8c2fcc39ce74f45eb3d02147595a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Analytical Chemistry</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Emulsions</topic><topic>Engineering</topic><topic>Engineering Fluid Dynamics</topic><topic>Flow rates</topic><topic>Internal water</topic><topic>Nanotechnology and Microengineering</topic><topic>Research Paper</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Josephides, Dimitris N.</creatorcontrib><creatorcontrib>Sajjadi, Shahriar</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 2: Ocean Technology, Policy & Non-Living Resources</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>ProQuest Engineering Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Engineering Database</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>DELNET Engineering & Technology Collection</collection><collection>Aqualine</collection><collection>Water Resources Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Microfluidics and nanofluidics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Josephides, Dimitris N.</au><au>Sajjadi, Shahriar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Microfluidic method for creating monodisperse viscous single emulsions via core–shell templating</atitle><jtitle>Microfluidics and nanofluidics</jtitle><stitle>Microfluid Nanofluid</stitle><date>2015-03-01</date><risdate>2015</risdate><volume>18</volume><issue>3</issue><spage>383</spage><epage>390</epage><pages>383-390</pages><issn>1613-4982</issn><eissn>1613-4990</eissn><abstract>Creating droplets with viscous media in microfluidic devices is extremely problematic due to the early onset of jetting. This report presents a method of creating highly monodisperse single emulsions of high viscosity (≈100 cP for both dispersed and continuous phases) using glass-based microfluidics. This method utilises a three-phase flow technique, where internal water droplets are introduced into a would-be-jetting oil stream forcing the system into a quasi-dripping regime to produce highly monodisperse core–shell drops that later rupture to form single drops. Emulsions with droplet diameters between 75 and 120 μm with a
C
v
< 2 % were created at flow rates of up to 500 μl/h using this three-phase technique where similar emulsions using the standard two-phase technique could not be obtained. The rate of addition of internal droplets to induce a quasi-dripping mode was found to be similar to the dominant perturbation frequencies required to rupture a jet according to Plateau–Rayleigh instability theory.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1007/s10404-014-1439-2</doi><tpages>8</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1613-4982 |
ispartof | Microfluidics and nanofluidics, 2015-03, Vol.18 (3), p.383-390 |
issn | 1613-4982 1613-4990 |
language | eng |
recordid | cdi_proquest_miscellaneous_1705064408 |
source | SpringerLink Journals |
subjects | Analytical Chemistry Biomedical Engineering and Bioengineering Emulsions Engineering Engineering Fluid Dynamics Flow rates Internal water Nanotechnology and Microengineering Research Paper |
title | Microfluidic method for creating monodisperse viscous single emulsions via core–shell templating |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T10%3A35%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Microfluidic%20method%20for%20creating%20monodisperse%20viscous%20single%20emulsions%20via%20core%E2%80%93shell%20templating&rft.jtitle=Microfluidics%20and%20nanofluidics&rft.au=Josephides,%20Dimitris%20N.&rft.date=2015-03-01&rft.volume=18&rft.issue=3&rft.spage=383&rft.epage=390&rft.pages=383-390&rft.issn=1613-4982&rft.eissn=1613-4990&rft_id=info:doi/10.1007/s10404-014-1439-2&rft_dat=%3Cproquest_cross%3E1705064408%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1658840884&rft_id=info:pmid/&rfr_iscdi=true |