Microfluidic method for creating monodisperse viscous single emulsions via core–shell templating

Creating droplets with viscous media in microfluidic devices is extremely problematic due to the early onset of jetting. This report presents a method of creating highly monodisperse single emulsions of high viscosity (≈100 cP for both dispersed and continuous phases) using glass-based microfluidics...

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Veröffentlicht in:Microfluidics and nanofluidics 2015-03, Vol.18 (3), p.383-390
Hauptverfasser: Josephides, Dimitris N., Sajjadi, Shahriar
Format: Artikel
Sprache:eng
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Zusammenfassung:Creating droplets with viscous media in microfluidic devices is extremely problematic due to the early onset of jetting. This report presents a method of creating highly monodisperse single emulsions of high viscosity (≈100 cP for both dispersed and continuous phases) using glass-based microfluidics. This method utilises a three-phase flow technique, where internal water droplets are introduced into a would-be-jetting oil stream forcing the system into a quasi-dripping regime to produce highly monodisperse core–shell drops that later rupture to form single drops. Emulsions with droplet diameters between 75 and 120 μm with a C v  
ISSN:1613-4982
1613-4990
DOI:10.1007/s10404-014-1439-2