Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study

Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study

BackgroundThere is limited data on the risk factors and phenotypical characteristics associated with spirometrically confirmed COPD in never-smokers in the general population.AimsTo compare the characteristics associated with COPD by gender and by severity of airway obstruction in never-smokers and...

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Veröffentlicht in:Thorax 2015-09, Vol.70 (9), p.822-829
Hauptverfasser: Tan, W C, Sin, D D, Bourbeau, J, Hernandez, P, Chapman, K R, Cowie, R, FitzGerald, J M, Marciniuk, D D, Maltais, F, Buist, A S, Road, J, Hogg, J C, Kirby, M, Coxson, H, Hague, C, Leipsic, J, O'Donnell, D E, Aaron, S D
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Airway Obstruction - physiopathology
Biomass energy
Canada
Cross-Sectional Studies
Emphysema
Female
Gender differences
Hospitalization
Humans
Logistic Models
Lung - physiopathology
Lung diseases
Male
Medical imaging
Middle Aged
Physiology
Population-based studies
Prevalence
Prospective Studies
Pulmonary Disease, Chronic Obstructive - physiopathology
Risk Factors
Smoking
Smoking - adverse effects
Spirometry
Tobacco Smoke Pollution - adverse effects
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Zusammenfassung:BackgroundThere is limited data on the risk factors and phenotypical characteristics associated with spirometrically confirmed COPD in never-smokers in the general population.AimsTo compare the characteristics associated with COPD by gender and by severity of airway obstruction in never-smokers and in ever-smokers.MethodWe analysed the data from 5176 adults aged 40 years and older who participated in the initial cross-sectional phase of the population-based, prospective, multisite Canadian Cohort of Obstructive Lung Disease study. Never-smokers were defined as those with a lifetime exposure of
ISSN:0040-6376
1468-3296
DOI:10.1136/thoraxjnl-2015-206938