Cytogenetic effects of occupational exposure in the peripheral blood lymphocytes of pesticide sprayers

The potential clastogenic effect of pesticides was investigated in 56 (29 indoor and 27 outdoor) agricultural workers exposed to complex chemical mixtures. Exposed and referent subjects were selected from the same geographical area located in Ionia, province of Thessaloniki, Greece. Chromosome aberr...

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Veröffentlicht in:	Carcinogenesis (New York) 1996-01, Vol.17 (1), p.99-101
Hauptverfasser:	Kourakis, Anastasions, Mouratidou, Maria, Barbouti, Aikaterini, Dimikiotou, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosome Aberrations Female Humans Lymphocytes - drug effects Lymphocytes - ultrastructure Male Medical sciences Occupational Exposure - adverse effects Pesticides - toxicity Pesticides, fertilizers and other agrochemicals toxicology Toxicology
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Beschreibung
Zusammenfassung:	The potential clastogenic effect of pesticides was investigated in 56 (29 indoor and 27 outdoor) agricultural workers exposed to complex chemical mixtures. Exposed and referent subjects were selected from the same geographical area located in Ionia, province of Thessaloniki, Greece. Chromosome aberrations (CA) and sister chromatid exchanges (SCE), were studied in peripheral lymphocytes. Comparison between workers and control group revealed that the individuals exposed to pesticieds showed substantial clastogenic effects (CA = 2.66% compared to 0.53%, P
ISSN:	0143-3334 1460-2180
DOI:	10.1093/carcin/17.1.99