Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood

Highlights • Prenatal stress increases respiratory instability in adult offspring. • Prenatal stress affects ventilatory responses to hypoxia and hypercapnia. • Prenatal stress induces a basal state of hypertension and enhances the HPA axis response to stress. • Prenatal stress causes a deficit in innervation density of distal colon. • Prenatal stress has long-term effects on microbial intestinal colonisation.