Burden of invasive pneumococcal disease (IPD) in Sri-Lanka: Deriving a reasonable measure for vaccine introduction decision making

Highlights • Lack of disease burden data is an obstacle for pneumococcal vaccine introduction decision-making. • A population-based study and sentinel surveillance data were used to derive an incidence estimate. • The estimate of invasive pneumococcal pneumonia and sepsis based on low-sensitive, culture confirmation was adjusted by a correction factor. • Estimate lies in middle between low European and high Bangladesh, African estimates.