Total tumor volume and alpha‐fetoprotein for selection of transplant candidates with hepatocellular carcinoma: A prospective validation

The selection of liver transplantation (LT) candidates with hepatocellular carcinoma (HCC) is currently validated based on Milan criteria. The use of extended criteria has remained a matter of debate, mainly because of the absence of prospective validation. The present prospective study recruited pa...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 2015-07, Vol.62 (1), p.158-165
Hauptverfasser: Toso, Christian, Meeberg, Glenda, Hernandez‐Alejandro, Roberto, Dufour, Jean‐François, Marotta, Paul, Majno, Pietro, Kneteman, Norman M.
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Sprache:eng
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Zusammenfassung:The selection of liver transplantation (LT) candidates with hepatocellular carcinoma (HCC) is currently validated based on Milan criteria. The use of extended criteria has remained a matter of debate, mainly because of the absence of prospective validation. The present prospective study recruited patients according to the previously proposed total tumor volume (TTV; ≤115 cm3)/alpha‐fetoprotein (AFP; ≤400 ng/mL) score. Patients with AFP >400 ng/mL were excluded, and, as such, the Milan group was modified to include only patients with AFP
ISSN:0270-9139
1527-3350
DOI:10.1002/hep.27787