Survival benefit in women with BRCA1 mutation or familial risk in the MRI screening study (MRISC)

Adding MRI to annual mammography screening improves early breast cancer detection in women with familial risk or BRCA1/2 mutation, but breast cancer specific metastasis free survival (MFS) remains unknown. We compared MFS of patients from the largest prospective MRI Screening Study (MRISC) with 1:1...

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Veröffentlicht in:	International journal of cancer 2015-10, Vol.137 (7), p.1729-1738
Hauptverfasser:	Saadatmand, Sepideh, Obdeijn, Inge‐Marie, Rutgers, Emiel J., Oosterwijk, Jan C., Tollenaar, Rob A., Woldringh, Gwendolyn H., Bergers, Elisabeth, Verhoef, Cornelis, Heijnsdijk, Eveline A., Hooning, Maartje J., de Koning, Harry J., Tilanus‐Linthorst, Madeleine M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged BRCA1 BRCA2 Breast cancer breast cancer survival Breast Neoplasms - genetics Breast Neoplasms - mortality Cancer Case-Control Studies familial cancer syndromes Female Genes, BRCA1 Genetic Predisposition to Disease Health risk assessment Humans Magnetic Resonance Imaging - methods Mammography Medical research Metastasis Middle Aged Mutation Netherlands - epidemiology Prospective Studies screening
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Zusammenfassung:	Adding MRI to annual mammography screening improves early breast cancer detection in women with familial risk or BRCA1/2 mutation, but breast cancer specific metastasis free survival (MFS) remains unknown. We compared MFS of patients from the largest prospective MRI Screening Study (MRISC) with 1:1 matched controls. Controls, unscreened if
ISSN:	0020-7136 1097-0215
DOI:	10.1002/ijc.29534