Implementation and Operational Research: Effects of CD4 Monitoring Frequency on Clinical End Points in Clinically Stable HIV-Infected Patients With Viral Suppression

Current treatment guidelines for HIV infection recommend routine CD4 lymphocyte (CD4) count monitoring in patients with viral suppression. This may have a limited impact on influencing care as clinically meaningful CD4 decline rarely occurs during viral suppression. In a regional HIV observational c...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2015-07, Vol.69 (3), p.e85-e92
Hauptverfasser:	Ahn, Jin Young, Boettiger, David, Law, Matthew, Kumarasamy, Nagalingeswaran, Yunihastuti, Evy, Chaiwarith, Romanee, Lee, Man Po, Sim, Benedict L H, Oka, Shinichi, Wong, Wingwai, Kamarulzaman, Adeeba, Kantipong, Pacharee, Phanuphak, Praphan, Ng, Oon Tek, Kiertiburanakul, Sasisopin, Zhang, Fujie, Pujari, Sanjay, Ditangco, Rossana, Ratanasuwan, Winai, Merati, Tuti Parwati, Saphonn, Vonthanak, Sohn, Annette H, Choi, Jun Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Anti-HIV Agents - administration & dosage Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use CD4 Lymphocyte Count Cohort Studies Comparative analysis Confidence intervals Disease management Female HIV HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 - drug effects HIV-1 - immunology Human immunodeficiency virus Humans Lymphocytes Male Middle Aged Virology
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Beschreibung
Zusammenfassung:	Current treatment guidelines for HIV infection recommend routine CD4 lymphocyte (CD4) count monitoring in patients with viral suppression. This may have a limited impact on influencing care as clinically meaningful CD4 decline rarely occurs during viral suppression. In a regional HIV observational cohort in the Asia-Pacific region, patients with viral suppression (2 consecutive viral loads
ISSN:	1525-4135 1944-7884
DOI:	10.1097/QAI.0000000000000634