NCI-MATCH trial pushes cancer umbrella trial paradigm

An umbrella trial of 25 targeted treatments in all cancer types tackles treatment selection on the basis of genetic events rather than by tumour histology. An umbrella trial of 25 targeted treatments in all cancer types tackles treatment selection on the basis of genetic events rather than by tumour...

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Veröffentlicht in:	Nature reviews. Drug discovery 2015-08, Vol.14 (8), p.513-515
1. Verfasser:	Mullard, Asher
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154/109 631/208 631/67 692/308/153 Antineoplastic Agents - pharmacology Biomedicine Biotechnology Cancer Research Clinical Trials as Topic - methods Genetic Testing - methods Humans Mass Screening - methods Medicinal Chemistry Molecular Medicine Molecular Targeted Therapy National Cancer Institute (U.S.) Neoplasms - drug therapy Neoplasms - genetics news-and-analysis Pharmacology/Toxicology United States
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Beschreibung
Zusammenfassung:	An umbrella trial of 25 targeted treatments in all cancer types tackles treatment selection on the basis of genetic events rather than by tumour histology. An umbrella trial of 25 targeted treatments in all cancer types tackles treatment selection on the basis of genetic events rather than by tumour histology.
ISSN:	1474-1776 1474-1784
DOI:	10.1038/nrd4694