Chiral-at-Metal Octahedral Iridium Catalyst for the Asymmetric Construction of an All-Carbon Quaternary Stereocenter

Chiral-at-Metal Octahedral Iridium Catalyst for the Asymmetric Construction of an All-Carbon Quaternary Stereocenter

Metal‐templated organocatalysis: The enantioselective formation of an all‐carbon quaternary stereocenter is catalyzed by the ligand sphere of an inert bis‐cyclometalated iridium complex (see picture). In this complex, the metal‐centered chirality serves as the sole source for the effective asymmetri...

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Veröffentlicht in:Angewandte Chemie International Edition 2013-12, Vol.52 (52), p.14021-14025
Hauptverfasser: Chen, Liang-An, Tang, Xiaojuan, Xi, Jianwei, Xu, Weici, Gong, Lei, Meggers, Eric
Format: Artikel
Sprache:eng
Schlagworte:
asymmetric catalysis
Asymmetry
Carbon - chemistry
Catalysis
Chirality
Construction
Formations
hydrogen bonds
Inert
Iridium
Iridium - chemistry
Ligands
Peptides - chemistry
quaternary stereocenter
Sole
Stereoisomerism
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Beschreibung
Zusammenfassung:Metal‐templated organocatalysis: The enantioselective formation of an all‐carbon quaternary stereocenter is catalyzed by the ligand sphere of an inert bis‐cyclometalated iridium complex (see picture). In this complex, the metal‐centered chirality serves as the sole source for the effective asymmetric induction.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201306997