A Unique Family of Rigid Analogues of the GFP Chromophore with Tunable Two-Photon Action Cross-Sections for Biological Imaging
Conformationally restricted analogues of the GFP chromophore have been synthesized. The spectroscopic properties of GCTPOC, a unique family with tunable two‐photon action cross‐sections, were investigated. GCTPOC could be used as a robust two‐photon platform for development of a two‐photon fluoresce...
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| Veröffentlicht in: | Angewandte Chemie International Edition 2013-09, Vol.52 (38), p.10018-10022 |
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| container_end_page | 10022 |
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| container_issue | 38 |
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| container_title | Angewandte Chemie International Edition |
| container_volume | 52 |
| creator | Yuan, Lin Lin, Weiying Chen, Hua Zhu, Sasa He, Longwei |
| description | Conformationally restricted analogues of the GFP chromophore have been synthesized. The spectroscopic properties of GCTPOC, a unique family with tunable two‐photon action cross‐sections, were investigated. GCTPOC could be used as a robust two‐photon platform for development of a two‐photon fluorescent thiol sensor, which could stain endogenous thiols both in vitro and in vivo. |
| doi_str_mv | 10.1002/anie.201303179 |
| format | Article |
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The spectroscopic properties of GCTPOC, a unique family with tunable two‐photon action cross‐sections, were investigated. 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KGaA, Weinheim</rights><rights>Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</rights><rights>Copyright © 2013 WILEY-VCH Verlag GmbH & Co. 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Chem. Int. Ed</addtitle><description>Conformationally restricted analogues of the GFP chromophore have been synthesized. The spectroscopic properties of GCTPOC, a unique family with tunable two‐photon action cross‐sections, were investigated. 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| fulltext | fulltext |
| identifier | ISSN: 1433-7851 |
| ispartof | Angewandte Chemie International Edition, 2013-09, Vol.52 (38), p.10018-10022 |
| issn | 1433-7851 1521-3773 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Biomedical materials Chromophores Cross sections fluorescence imaging fluorescent dyes Fluorescent Dyes - chemistry fluorescent probes GFP chromophore analogues Green Fluorescent Proteins - chemistry In vivo testing In vivo tests Molecular Conformation Photons Platforms Spectrum Analysis Surgical implants Thiols two-photon dyes |
| title | A Unique Family of Rigid Analogues of the GFP Chromophore with Tunable Two-Photon Action Cross-Sections for Biological Imaging |
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