pH-Switchable Ampholytic Supramolecular Copolymers

pH-Switchable Ampholytic Supramolecular Copolymers

β‐sheet‐encoded anionic and cationic dendritic peptide amphiphiles form supramolecular copolymers when self‐assembled in a 1:1 feed ratio of the monomers. These ampholytic materials have been designed for on‐off polymerization in response to pH triggers. The cooperative supramolecular self‐assembly...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2013-09, Vol.52 (38), p.10097-10101
Hauptverfasser: Frisch, Hendrik, Unsleber, Jan Patrick, Lüdeker, David, Peterlechner, Martin, Brunklaus, Gunther, Waller, Mark, Besenius, Pol
Format: Artikel
Sprache:eng
Schlagworte:
Cationic
cooperativity
copolymerization
Copolymers
Hydrogen-Ion Concentration
Molecular Structure
Monomers
Peptides
pH switch
Polymerization
Polymers - chemical synthesis
Polymers - chemistry
Self assembly
stimuli-responsive behavior
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:β‐sheet‐encoded anionic and cationic dendritic peptide amphiphiles form supramolecular copolymers when self‐assembled in a 1:1 feed ratio of the monomers. These ampholytic materials have been designed for on‐off polymerization in response to pH triggers. The cooperative supramolecular self‐assembly process is switched on at a physiologically relevant pH value and can be switched off by increasing or decreasing the pH value.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201303810