The Power of Fluorogenic Probes

The Power of Fluorogenic Probes

A definite turn‐on: Turning on fluorescence only where successful labeling is happening sounds as desirable as delivering a drug only where the drug target resides. New fluorogenic xanthene derivatives from the Bertozzi research group are getting us closer to “magic bullet” dyes (see picture).

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Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2013-02, Vol.52 (9), p.2408-2410
Hauptverfasser: Nadler, André, Schultz, Carsten
Format: Artikel
Sprache:eng
Schlagworte:
Acoustics
Bullets
click reaction
Derivatives
Drug delivery systems
Drugs
Dyes
Fluorescence
Fluorescent Dyes - chemistry
fluorophores
in vivo chemistry
labeling reactions
Marking
microscopy
Microscopy, Fluorescence - methods
Spectrometry, Fluorescence - methods
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Beschreibung
Zusammenfassung:A definite turn‐on: Turning on fluorescence only where successful labeling is happening sounds as desirable as delivering a drug only where the drug target resides. New fluorogenic xanthene derivatives from the Bertozzi research group are getting us closer to “magic bullet” dyes (see picture).
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201209733