Successful Labeling of super( 99m)Tc-MDP Using super( 99m)Tc Separated from super( 99)Mo Produced by super( 100)Mo(n,2n) super( 99)Mo

We have for the first time succeeded in separating ... from a MoO ... sample irradiated with accelerator neutrons free from any radioactive impurities and in formulating ...-methylene diphosphonate ..., the mother nuclide of ..., was produced by the ... reaction using about 14 MeV neutrons provided...

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Veröffentlicht in:Journal of the Physical Society of Japan 2011-08, Vol.80 (8), p.1-1
Hauptverfasser: Nagai, Yasuki, Hatsukawa, Yuichi, Kin, Tadahiro, Hashimoto, Kazuyuki, Motoishi, Shoji, Konno, Chikara, Ochiai, Kentaro, Takakura, Kosuke, Sato, Yuichi, Kawauchi, Yukimasa, Sato, Norihito, Ohta, Akio, Yamabayashi, Hisamichi, Tanase, Masakazu, Fujisaki, Saburo, Teranaka, Tomoyuki, Takeuchi, Nobuhiro, Igarashi, Takashi
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Sprache:eng
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Zusammenfassung:We have for the first time succeeded in separating ... from a MoO ... sample irradiated with accelerator neutrons free from any radioactive impurities and in formulating ...-methylene diphosphonate ..., the mother nuclide of ..., was produced by the ... reaction using about 14 MeV neutrons provided by the ... reaction at the Fusion Neutronics Source of Japan Atomic Energy Agency. The ... was separated from ... by sublimation and its radionuclide purity was confirmed to be higher than 99.99% by ...-spectroscopy. The labeling efficiency of ... was shown to be higher than 99% by thin-layer chromatography. These values exceed the United States Pharmacopeia requirements for a fission product, ... Consequently, a ... radiopharmaceutical preparation formed by using the mentioned ... can be a promising substitute for the fission product ..., which is currently produced using a highly enriched uranium target in aging research reactors. A longstanding problem to ensure a reliable and constant supply of ... in Japan can be partially mitigated. (ProQuest: ... denotes formulae/symbols omitted.)
ISSN:0031-9015
1347-4073