Efficient Isolation and Accurate InSitu Analysis of Circulating Tumor Cells Using Detachable Beads and a High-Pore-Density Filter

Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and en...

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Veröffentlicht in:Angewandte Chemie International Edition 2013-08, Vol.52 (32), p.8337-8340
Hauptverfasser: Lee, Hun Joo, Oh, Jin Ho, Oh, Jin Mi, Park, Jong-Myeon, Lee, Jeong-Gun, Kim, Minseok S, Kim, Yeon Jeong, Kang, Hyun Ju, Jeong, Joon, Kim, Seung Il, Lee, Soo Suk, Choi, Jeong-Woo, Huh, Nam
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container_end_page 8340
container_issue 32
container_start_page 8337
container_title Angewandte Chemie International Edition
container_volume 52
creator Lee, Hun Joo
Oh, Jin Ho
Oh, Jin Mi
Park, Jong-Myeon
Lee, Jeong-Gun
Kim, Minseok S
Kim, Yeon Jeong
Kang, Hyun Ju
Jeong, Joon
Kim, Seung Il
Lee, Soo Suk
Choi, Jeong-Woo
Huh, Nam
description Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and enables accurate measurement of insitu protein-expression levels.
doi_str_mv 10.1002/anie.201302278
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source Wiley Journals
subjects Beads
Blood
Cancer
Circulating
Detaching
Proteins
Tumors
title Efficient Isolation and Accurate InSitu Analysis of Circulating Tumor Cells Using Detachable Beads and a High-Pore-Density Filter
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