Efficient Isolation and Accurate InSitu Analysis of Circulating Tumor Cells Using Detachable Beads and a High-Pore-Density Filter

Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and en...

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Veröffentlicht in:Angewandte Chemie International Edition 2013-08, Vol.52 (32), p.8337-8340
Hauptverfasser: Lee, Hun Joo, Oh, Jin Ho, Oh, Jin Mi, Park, Jong-Myeon, Lee, Jeong-Gun, Kim, Minseok S, Kim, Yeon Jeong, Kang, Hyun Ju, Jeong, Joon, Kim, Seung Il, Lee, Soo Suk, Choi, Jeong-Woo, Huh, Nam
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Sprache:eng
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Zusammenfassung:Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and enables accurate measurement of insitu protein-expression levels.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201302278