Gold Nanorods: Controlling Their Surface Chemistry and Complete Detoxification by a Two-Step Place Exchange

Gold Nanorods: Controlling Their Surface Chemistry and Complete Detoxification by a Two-Step Place Exchange

Surface functionalization: Complete detoxification of gold nanorods was achieved by manipulating the position in the stability map between surface‐adsorbing polyethylene glycol (PEG) and destabilizing ethanol (see picture). This robust procedure complements studies related to the effects of shape wh...

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Veröffentlicht in:Angewandte Chemie International Edition 2013-02, Vol.52 (7), p.1934-1938
Hauptverfasser: Kinnear, Calum, Dietsch, Hervé, Clift, Martin J. D., Endes, Carola, Rothen-Rutishauser, Barbara, Petri-Fink, Alke
Format: Artikel
Sprache:eng
Schlagworte:
colloids
Complement
cytotoxicity
Ethanol
Ethyl alcohol
Exchange
Gold
Gold - chemistry
Humans
Macrophages - drug effects
Macrophages - metabolism
Nanorods
Nanotubes - chemistry
Nanotubes - toxicity
Polyethylene glycol
Polyethylene Glycols - chemistry
polymers
Quaternary Ammonium Compounds - chemistry
Surface chemistry
Surface Properties
Tumor Necrosis Factor-alpha - metabolism
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Zusammenfassung:Surface functionalization: Complete detoxification of gold nanorods was achieved by manipulating the position in the stability map between surface‐adsorbing polyethylene glycol (PEG) and destabilizing ethanol (see picture). This robust procedure complements studies related to the effects of shape when contemplating the nanoparticle–cell interaction.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201208568