Automated Polysaccharide Synthesis: Assembly of a 30mer Mannoside

Automated Polysaccharide Synthesis: Assembly of a 30mer Mannoside

Automated carbohydrate synthesis breaks new grounds: The longest sugar chemically synthesized to date (a 30 mer) has been accessed. Key to the process is the use of a catch–release technique, which labels the saccharide, thus allowing it to be separated later through temporary attachement to magneti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2013-05, Vol.52 (22), p.5862-5865
Hauptverfasser: Calin, Oliviana, Eller, Steffen, Seeberger, Peter H.
Format: Artikel
Sprache:eng
Schlagworte:
Assembly
Automated
Automation
Carbohydrates
catch-release technique
Grounds
Labels
magnetic beads
Magnetics
Mannosides - chemical synthesis
Mannosides - chemistry
Molecular Structure
Polysaccharides
Polysaccharides - chemical synthesis
Polysaccharides - chemistry
Saccharides
solid-phase synthesis
Synthesis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Automated carbohydrate synthesis breaks new grounds: The longest sugar chemically synthesized to date (a 30 mer) has been accessed. Key to the process is the use of a catch–release technique, which labels the saccharide, thus allowing it to be separated later through temporary attachement to magnetic particles.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201210176