Combination of i-Motif and G-Quadruplex Structures within the Same Strand: Formation and Application

Combination of i-Motif and G-Quadruplex Structures within the Same Strand: Formation and Application

Peaceful coexistence: A double quadruplex composed of an i‐motif and a G‐quadruplex was constructed within one oligonucleotide strand (see picture). The defined double‐quadruplex structure can serve as a NOTIF logic gate on the basis of the fluorescence of crystal violet.

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Veröffentlicht in:Angewandte Chemie International Edition 2013-07, Vol.52 (30), p.7742-7746
Hauptverfasser: Zhou, Jun, Amrane, Samir, Korkut, Dursun Nizam, Bourdoncle, Anne, He, Hong-Zhang, Ma, Dik-Lung, Mergny, Jean-Louis
Format: Artikel
Sprache:eng
Schlagworte:
Circular Dichroism
Construction
Crystal structure
Fluorescence
Formations
G-Quadruplexes
Gates
i-motifs
logic gates
Nucleic Acid Conformation
Oligonucleotides
Oligonucleotides - chemistry
Pictures
Spectrometry, Fluorescence
Strands
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Beschreibung
Zusammenfassung:Peaceful coexistence: A double quadruplex composed of an i‐motif and a G‐quadruplex was constructed within one oligonucleotide strand (see picture). The defined double‐quadruplex structure can serve as a NOTIF logic gate on the basis of the fluorescence of crystal violet.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201301278