Domino Cycloaddition Organocascades of Dendralenes

Hooray Horeau! Highly enantioselective organocatalyzed Diels–Alder reaction cascades are disclosed for the first time. The reaction enables the efficient and rapid construction of enantiopure polycycles from simple achiral, acyclic polyenes.

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Veröffentlicht in:Angewandte Chemie International Edition 2013-08, Vol.52 (32), p.8333-8336
Hauptverfasser: Green, Nicholas J., Lawrence, Andrew L., Bojase, Gomotsang, Willis, Anthony C., Paddon-Row, Michael N., Sherburn, Michael S.
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container_end_page 8336
container_issue 32
container_start_page 8333
container_title Angewandte Chemie International Edition
container_volume 52
creator Green, Nicholas J.
Lawrence, Andrew L.
Bojase, Gomotsang
Willis, Anthony C.
Paddon-Row, Michael N.
Sherburn, Michael S.
description Hooray Horeau! Highly enantioselective organocatalyzed Diels–Alder reaction cascades are disclosed for the first time. The reaction enables the efficient and rapid construction of enantiopure polycycles from simple achiral, acyclic polyenes.
doi_str_mv 10.1002/anie.201302185
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subjects Cascades
Construction
Cycloaddition
Diels-Alder reactions
hydrocarbons
polycycles
polyenes
synthetic methods
title Domino Cycloaddition Organocascades of Dendralenes
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