Catalytic Generation and Selective Heterocoupling of Two Electron-Rich Alkenes

Complex heterocyclic products were synthesized from simple alkynamine and alkynol derivatives in a double cycloisomerization/heterodimerization cascade reaction (see scheme). The reaction includes the heterocoupling reaction of two different electron‐rich alkenes and leads to the formation of four new bonds and three stereocenters (two of them quaternary).