Lighting up Carbon Monoxide: Fluorescent Probes for Monitoring CO in Living Cells

Lighting up Carbon Monoxide: Fluorescent Probes for Monitoring CO in Living Cells

All aglow: Both a fluorescent biosensor, composed of a circularly permuted yellow fluorescent protein (cpYFP), and a small‐molecule fluorescent probe (1) for the detection of CO in living cells have been recently reported. Though different these novel probes were designed based on the unique binding...

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Veröffentlicht in:Angewandte Chemie International Edition 2013-02, Vol.52 (6), p.1628-1630
Hauptverfasser: Yuan, Lin, Lin, Weiying, Tan, Li, Zheng, Kaibo, Huang, Weimin
Format: Artikel
Sprache:eng
Schlagworte:
Bacterial Proteins - chemistry
Binding
Biosensors
Carbon monoxide
Carbon Monoxide - chemistry
Circularity
Fluorescent Dyes - chemistry
fluorescent probes
Hemeproteins - chemistry
Humans
Illumination
imaging agents
Lighting
Monitoring
Proteins
sensing
Trans-Activators - chemistry
transition metals
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Beschreibung
Zusammenfassung:All aglow: Both a fluorescent biosensor, composed of a circularly permuted yellow fluorescent protein (cpYFP), and a small‐molecule fluorescent probe (1) for the detection of CO in living cells have been recently reported. Though different these novel probes were designed based on the unique binding ability of CO to transition‐metal ions.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201208346