Intermolecular Domino Reaction of Two Aryl Iodides Involving Two CH Functionalizations

A palladium‐catalyzed intermolecular cross‐coupling of two aryl iodides is reported, giving polycyclic ring systems with a high level of convergence and efficiency. Pendulum Reaction: 1 Pd complex catalyzes the intermolecular reaction of 2 aryl iodides to form 3 new CC bonds through 2 CH activations and 1 carbopalladation. The intermolecular domino reaction of two aryl iodides gives fused biaryls with a high level of convergence and efficiency. The key to success lies in the choice of an appropriate bulky Pd catalyst, which allows the aryl iodides to be distinguished in the key step.