BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes

The fastest and the brightest: A new design that intimately connects tetrazine to a BODIPY fluorophore enables exceptionally efficient energy transfer and quenching. Upon reaction of the tetrazine, the brightness of the fluorophore increases more than a thousand‐fold, which is a fluorogenic activati...

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Veröffentlicht in:	Angewandte Chemie International Edition 2013-07, Vol.52 (27), p.6917-6920
Hauptverfasser:	Carlson, Jonathan C. T., Meimetis, Labros G., Hilderbrand, Scott A., Weissleder, Ralph
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Boron Compounds - chemical synthesis Boron Compounds - chemistry Brightness Chemical compounds Click Chemistry Derivatives Energy transfer Fluorescence Fluorescent Dyes fluorescent probes fluorogenic probes Molecular Structure Quenching Spectrometry, Fluorescence - methods tetrazines Tetrazoles - chemistry
Online-Zugang:	Volltext
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