Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of α,α-Dialkyl-α-Amino Acids

α,α‐Disubstituted α‐amino acids are central to biotechnological and biomedical chemical processes for their own sake and as substructures of biologically active molecules for diverse biomedical applications. Structurally, these compounds contain a quaternary stereocenter, which is particularly chall...

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Veröffentlicht in:Angewandte Chemie International Edition 2015-03, Vol.54 (10), p.3013-3017
Hauptverfasser: Hernandez, Karel, Zelen, Igor, Petrillo, Giovanna, Usón, Isabel, Wandtke, Claudia M., Bujons, Jordi, Joglar, Jesús, Parella, Teodor, Clapés, Pere
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Sprache:eng
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