Total Synthesis of (±)-HippolachninA
The first total synthesis of the marine polyketide (±)-hippolachninA has been achieved in nine linear steps and an overall yield of 9%. Rapid access to the oxacyclobutapentalene core structure was secured by strategic application of an ene cyclization.
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| Veröffentlicht in: | Angewandte Chemie International Edition 2015-02, Vol.54 (8), p.2378-2382 |
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| container_end_page | 2382 |
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| container_issue | 8 |
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| container_title | Angewandte Chemie International Edition |
| container_volume | 54 |
| creator | Ruider, Stefan A Sandmeier, Tobias Carreira, Erick M |
| description | The first total synthesis of the marine polyketide (±)-hippolachninA has been achieved in nine linear steps and an overall yield of 9%. Rapid access to the oxacyclobutapentalene core structure was secured by strategic application of an ene cyclization. |
| doi_str_mv | 10.1002/anie.201410419 |
| format | Article |
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| identifier | ISSN: 1433-7851 |
| ispartof | Angewandte Chemie International Edition, 2015-02, Vol.54 (8), p.2378-2382 |
| issn | 1433-7851 1521-3773 |
| language | eng |
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| source | Access via Wiley Online Library |
| subjects | Marine Synthesis |
| title | Total Synthesis of (±)-HippolachninA |
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