Electrochemical detection of single E. coli bacteria labeled with silver nanoparticles

A proof-of-concept for the electrochemical detection of single Escherichia coli bacteria decorated with silver nanoparticles is reported. Impacts of bacteria with an electrode - held at a suitably oxidizing potential - lead to an accompanying burst of current with each collision event. The frequency...

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Veröffentlicht in:	Biomaterials science 2015-06, Vol.3 (6), p.816-820
Hauptverfasser:	Sepunaru, Lior, Tschulik, Kristina, Batchelor-McAuley, Christopher, Gavish, Rachel, Compton, Richard G
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Electrodes Escherichia coli - chemistry Escherichia coli - metabolism Metal Nanoparticles - chemistry Oxidation-Reduction Silver - chemistry
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Zusammenfassung:	A proof-of-concept for the electrochemical detection of single Escherichia coli bacteria decorated with silver nanoparticles is reported. Impacts of bacteria with an electrode - held at a suitably oxidizing potential - lead to an accompanying burst of current with each collision event. The frequency of impacts scales with the concentration of bacteria and the charge indicates the extent of decoration.
ISSN:	2047-4830 2047-4849
DOI:	10.1039/c5bm00114e