Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy

Highlights • Autonomic changes following a GTC were measured using a wrist-worn sensor. • Adult patients had longer durations of post-ictal generalized EEG suppression. • The duration of post-itcal suppression correlated with the degree of sympathetic activation. • Post-ictal sympathetic and parasym...

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Veröffentlicht in:	Epilepsy research 2015-09, Vol.115, p.113-118
Hauptverfasser:	Sarkis, Rani A, Thome-Souza, Sigride, Poh, Ming-Zher, Llewellyn, Nichelle, Klehm, Jacquelyn, Madsen, Joseph R, Picard, Rosalind, Pennell, Page B, Dworetzky, Barbara A, Loddenkemper, Tobias, Reinsberger, Claus
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aging - physiology Autonomic nervous system Brain - physiopathology Child Electrocardiography Electrodermal activity Electroencephalography Epilepsy, Generalized - physiopathology Female Galvanic Skin Response - physiology Generalized tonic clonic seizures Heart Rate - physiology Humans Male Middle Aged Monitoring, Physiologic Neurology Post-ictal generalized EEG suppression Prospective Studies Seizures - physiopathology Sudden unexpected death in epilepsy Time Factors Young Adult
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Zusammenfassung:	Highlights • Autonomic changes following a GTC were measured using a wrist-worn sensor. • Adult patients had longer durations of post-ictal generalized EEG suppression. • The duration of post-itcal suppression correlated with the degree of sympathetic activation. • Post-ictal sympathetic and parasympathetic markers differed depending on age.
ISSN:	0920-1211 1872-6844
DOI:	10.1016/j.eplepsyres.2015.06.005