Failure of Cefotaxime Treatment in a Patient with Penicillin-Resistant Pneumococcal Meningitis and Confirmation of Nosocomial Spread by Random Amplified Polymorphic DNA Analysis

We report what is to our knowledge the first case of cefotaxime treatment failing in a patient with penicillin-resistant Streptococcus pneumoniae (PRSP) meningitis that was associated with nosocomial spread, as confirmed by DNA fingerprinting with use of randomly amplified polymorphic DNA (RAPD) ana...

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Veröffentlicht in:Clinical infectious diseases 1995-07, Vol.21 (1), p.234-235
Hauptverfasser: Raymond, Josette, Bingen, Edouard, Doit, Catherine, Brahimi, Naïma, Bergeret, Michel, Badoual, Jean, Gendrel, Dominique
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container_end_page 235
container_issue 1
container_start_page 234
container_title Clinical infectious diseases
container_volume 21
creator Raymond, Josette
Bingen, Edouard
Doit, Catherine
Brahimi, Naïma
Bergeret, Michel
Badoual, Jean
Gendrel, Dominique
description We report what is to our knowledge the first case of cefotaxime treatment failing in a patient with penicillin-resistant Streptococcus pneumoniae (PRSP) meningitis that was associated with nosocomial spread, as confirmed by DNA fingerprinting with use of randomly amplified polymorphic DNA (RAPD) analysis.
doi_str_mv 10.1093/clinids/21.1.234
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source MEDLINE; Oxford University Press Journals Digital Archive Legacy; Jstor Complete Legacy
subjects Antibiotics
Base Sequence
Cefotaxime - therapeutic use
Cephalosporins
Cephalosporins - therapeutic use
Correspondence
Cross Infection - diagnosis
Cross Infection - microbiology
DNA
DNA fingerprinting
DNA Primers - chemistry
DNA, Bacterial - analysis
Drug Therapy, Combination - therapeutic use
Female
Genetic polymorphism
Gentamicins - therapeutic use
Hospital beds
Humans
Infant
Meningitis, Pneumococcal - diagnosis
Meningitis, Pneumococcal - therapy
Molecular Sequence Data
Pediatrics
Penicillin Resistance
Pneumococcal meningitis
Polymerase chain reaction
Polymerase Chain Reaction - methods
Polymorphism, Restriction Fragment Length
Streptococcus pneumoniae
Streptococcus pneumoniae - genetics
Treatment Failure
Vancomycin - therapeutic use
title Failure of Cefotaxime Treatment in a Patient with Penicillin-Resistant Pneumococcal Meningitis and Confirmation of Nosocomial Spread by Random Amplified Polymorphic DNA Analysis
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